TRIM2 Monoclonal antibody, PBS Only (Capture)

TRIM2 Monoclonal Antibody for WB, IHC, IF-P, Cytometric bead array, Indirect ELISA
Cat No. 67342-1-PBS

产品说明书

CloneNo. 1H9C2

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat, pig

应用

WB, IHC, IF-P, Cytometric bead array, Indirect ELISA

1H9C2, E3 ubiquitin-protein ligase TRIM2, EC:2.3.2.27, KIAA0517, RING-type E3 ubiquitin transferase TRIM2

缓冲液配方:  PBS Only
偶联物:  Unconjugated
规格价格库存


产品信息

67342-1-PBS targets TRIM2 as part of a matched antibody pair:

MP51520-1: 67342-1-PBS capture and 67342-2-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, IHC, IF-P, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human, mouse, rat, pig
免疫原

CatNo: Ag14637

Product name: Recombinant human TRIM2 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-300 aa of BC011052

Sequence: MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLD

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 tripartite motif-containing 2
别名 1H9C2, E3 ubiquitin-protein ligase TRIM2, EC:2.3.2.27, KIAA0517, RING-type E3 ubiquitin transferase TRIM2
计算分子量 744 aa, 82 kDa
观测分子量 70-85 kDa
GenBank蛋白编号BC011052
基因名称 TRIM2
Gene ID (NCBI) 23321
RRIDAB_2882600
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ9C040
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tripartite motif-containing 2(TRIM2) is an E3 ubiquitin ligase which directs proteasome-mediated degradation of target proteins by the ubiquitination of NEFL and phosphorylation of BCL2L11. This protein contains an N-terminal RING domain, followed by a B-box-2 domain, a coiled-coil region, and 6 C-terminal NHL repeats. TRIM2 involves in the apoptotic response to ischemia via directing degradation of BIM protein, thus has a role in neuroprotection.

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