• Featured Product
  • KD/KO Validated

TRIB3 Polyclonal antibody

TRIB3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, ELISA and More (3)

Conjugate

Unconjugated

Cat No : 13300-1-AP

Print datasheet

Synonyms

C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3



经过测试的应用

Positive WB detected inL02 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13300-1-AP targets TRIB3 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA
Cited ApplicationsWB, IP, IF, IHC
Tested Reactivity human
Cited Reactivityhuman, monkey
Immunogen TRIB3 fusion protein Ag4085 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name tribbles homolog 3 (Drosophila)
Synonyms C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3
Calculated Molecular Weight 358 aa, 40 kDa
Observed Molecular Weight 40-45 kDa
GenBank Accession NumberBC027484
Gene Symbol TRIB3
Gene ID (NCBI) 57761
RRIDAB_10641988
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96RU7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TRIB3 is a pseudokinase molecule that affects a number of cellular functions. TRIB3 has been reported to be highly activated in the presence of a variety of stressors, including the deprivation of neurotrophic factors, hypoxia, and ER stress.TRIB3 protein is associated with a good prognosis in human breast cancer patients, possibly due to the fact that TRIB3 is involved in hypoxia tolerance.(PMID: 21704407). TRIB3 protein predicted molecular weights is approximately 39~45 kDa.(PMID: 31191318, PMID: 24414038, PMID: 31578236).

实验方案

Product Specific Protocols
WB protocol for TRIB3 antibody 13300-1-APDownload protocol
IF protocol for TRIB3 antibody 13300-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
WB,IP

J Cachexia Sarcopenia Muscle

Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles.

Authors - Guo-Kai Shang
monkeyIHC

Aging Dis

Age-Related Decline in Expression of Molecular Chaperones Induces Endoplasmic Reticulum Stress and Chondrocyte Apoptosis in Articular Cartilage.

Authors - Li Tan
humanWB

Autophagy

Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.

Authors - Tengfei Huang
  • KD Validated
humanWB,IF

Clin Cancer Res

PMID: 31235507

Authors - Jian Lin
  • KD Validated
WB

EMBO Rep

Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos.

Authors - Nadège Poncet
humanWB

Oxid Med Cell Longev

Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis

Authors - Lili Shi
  • KD Validated