验证数据展示
产品信息
27899-1-PBS targets TRIB1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IHC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag27541 Product name: Recombinant human TRIB1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-150 aa of BC063292 Sequence: MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYLSPPGSPCSPQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNITGIVEVI 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | tribbles homolog 1 (Drosophila) |
| 别名 | C8FW, GIG 2, GIG2, GIG-2, G-protein-coupled receptor-induced gene 2 protein |
| 计算分子量 | 372 aa, 41 kDa |
| 观测分子量 | 41 kDa |
| GenBank蛋白编号 | BC063292 |
| 基因名称 | TRIB1 |
| Gene ID (NCBI) | 10221 |
| RRID | AB_3742266 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q96RU8 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TRIB1, a pseudokinase encoded by the tribbles homolog 1 gene, regulates hepatic lipogenesis and lipid metabolism by modulating C/EBPα degradation, thereby influencing plasma lipid profiles and atherosclerotic risk. It is expressed in macrophages and vascular smooth muscle cells, linking metabolic and inflammatory pathways in cardiometabolic disorders (PMID: 26517927, PMID: 40331689).


