验证数据展示
产品信息
20752-1-PBS targets TRAPPC5 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag13185 Product name: Recombinant human TRAPPC5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-188 aa of BC042161 Sequence: MEARFTRGKSALLERALARPRTEVSLSAFALLFSELVQHCQSRVFSVAELQSRLAALGRQVGARVLDALVAREKGARRETKVLGALLFVKGAVWKALFGKEADKLEQANDDARTFYIIEREPLINTYISVPKENSTLNCASFTAGIVEAVLTHSGFPAKVTAHWHKGTTLMIKFEEAVIARDRALEGR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | trafficking protein particle complex 5 |
| 别名 | TRAPPC 5, Trafficking protein particle complex subunit 5 |
| 计算分子量 | 188 aa, 21 kDa |
| 观测分子量 | 21-23 kDa |
| GenBank蛋白编号 | BC042161 |
| 基因名称 | TRAPPC5 |
| Gene ID (NCBI) | 126003 |
| RRID | AB_3742003 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8IUR0 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Transport protein particle (TRAPP, also known as trafficking protein particle), a multimeric guanine nucleotide-exchange factor, regulates multiple membrane trafficking pathways (PMID: 20966969). TRAPPC5 is a component of the TRAPP complexes and is involved in processes such as intracellular vesicle transport. In hepatocellular carcinoma, upregulated expression of TRAPPC5 can enhance cancer cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) and promote tumorigenesis (PMID: 35425722).
