×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of Jurkat using 18110-1-AP (same clone as 18110-1-PBS)

    WB analysis of Jurkat using 18110-1-AP (same clone as 18110-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 18110-1-AP (TRAF3IP3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18110-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse thymus using 18110-1-AP (same clone as 18110-1-PBS)

    WB analysis of mouse thymus using 18110-1-AP (same clone as 18110-1-PBS)

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with 18110-1-AP (TRAF3IP3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18110-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 18110-1-AP (same clone as 18110-1-PBS)

    IHC staining of human colon cancer using 18110-1-AP (same clone as 18110-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 18110-1-AP (TRAF3IP3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18110-1-PBS in a different storage buffer formulation.

TRAF3IP3 Polyclonal antibody, PBS Only

TRAF3IP3 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 18110-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

18110-1-PBS targets TRAF3IP3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag12559

Product name: Recombinant human TRAF3IP3 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-353 aa of BC110302

Sequence: MISPDPRPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTVLKEPLSCARRISSPREQVTGTSSEVFPAQHPPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQIN

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 TRAF3 interacting protein 3
别名
计算分子量353aa,41 kDa; 551aa,64 kDa
观测分子量64 kDa, 47 kDa, 41 kDa
GenBank蛋白编号BC110302
基因名称 TRAF3IP3
Gene ID (NCBI) 80342
RRIDAB_2918057
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y228
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TRAF3 interacting protein 3 (TRAF3IP3) is an essential adapter protein containing a coiled-coil domain that affects both innate and adaptive immunity. It plays a crucial role in the regulation of thymocyte development (PMID:26195727), and it also regulates T-cell stability and function by recruiting the serine-threonine phosphatase catalytic subunit (PPP2CA) to the lysosome, thereby facilitating the interaction of PP2Ac with the mTORC1 component RPTOR and restricting glycolytic metabolism (PMID:30115741). TRAF3IP3 responses to viral infection, facilitates the recruitment of TRAF3 to MAVS within mitochondria leading to IRF3 activation and interferon production (PMID:31390091). TRAF3IP3 has 3 isoforms produced by alternative splicing with the molecular weight of 64 kDa, 47 kDa and 41 kDa.

||
New chat

Able™

正在加载，请稍候...