TMP195

CAS号

1314891-22-9

分子式

C23H19F3N4O3

主要靶点

HDAC

仅限科研使用

Cat No : CM04437

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Synonyms

Histone deacetylases|HDAC|HDAC4|HDAC5|HDAC7|HDAC9|inhibit|Inhibitor|TFMO 2|TFMO2|TFMO-2|TMP195|TMP-195|TMP 195



产品信息

CAS号 1314891-22-9
分子式 C23H19F3N4O3
主要靶点 HDAC
主要通路 DNA 损伤和修复|表观遗传
分子量 456.42
纯度 98.92%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Histone deacetylases|HDAC|HDAC4|HDAC5|HDAC7|HDAC9|inhibit|Inhibitor|TFMO 2|TFMO2|TFMO-2|TMP195|TMP-195|TMP 195

靶点活性

HDAC9:15 nM(Ki)|HDAC5:60 nM(Ki)|HDAC7:26 nM(Ki)|HDAC4:59 nM(Ki)

溶解度

DMSO:82 mg/mL (179.66 mM)

参考文献

1.Lobera M., et al. Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group. Nat Chem Biol. 2013 May;9(5):319-25.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2