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验证数据展示

  • WB analysis of A2780 using 60195-1-Ig (same clone as 60195-1-PBS)

    WB analysis of A2780 using 60195-1-Ig (same clone as 60195-1-PBS)

    A2780 cells were subjected to SDS PAGE followed by western blot with 60195-1-Ig (TMEM70 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

    IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver using 60195-1-Ig(TMEM70 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

    IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver using 60195-1-Ig(TMEM70 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 60195-1-Ig (same clone as 60195-1-PBS)

    WB analysis of HeLa using 60195-1-Ig (same clone as 60195-1-PBS)

    WB result of TMEM70 antibody (60195-1-Ig; 1:1500; incubated at room temperature for 1.5 hours) with sh-Control and sh-TMEM70 transfected HeLa cells. This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

  • Featured Product
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TMEM70 Monoclonal antibody, PBS Only

TMEM70 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 60195-1-PBS

产品说明书

CloneNo. 2C11C3

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

TMEM70, transmembrane protein 70

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

60195-1-PBS targets TMEM70 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag16947

Product name: Recombinant human TMEM70 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 148-260 aa of BC002748

Sequence: MGSFTVITPVLLHFITKGYVIRLYHEATTDTYKAITYNAMLAETSTVFHQNDVKIPDAKHVFTTFYAKTKSLLVNPVLFPNREDYIHLMGYDKEEFILYMEETSEEKRHKDDK

种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 transmembrane protein 70
别名 TMEM70, transmembrane protein 70
计算分子量 260 aa, 29 kDa
观测分子量 18 kDa
GenBank蛋白编号BC002748
基因名称 TMEM70
Gene ID (NCBI) 54968
RRIDAB_10896316
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9BUB7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TMEM70 belongs to the TMEM70 family. It is involved in biogenesis of mitochondrial ATP synthase. Defects in TMEM70 are a cause of mitochondrial encephalocardiomyopathy neonatal due to ATP synthase deficiency (MT-ATPSD). A publication (PMID:21147908) identified TMEM70 gene defect as a pan-ethnic disorder and further redefined it as the most common cause of nuclear-origin ATP synthase deficiency.

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