TMEM231 Polyclonal antibody

TMEM231 Polyclonal Antibody for IHC, IF/ICC, ELISA
Cat No. 23731-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, canine

应用

IHC, IF/ICC, ELISA

ALYE870, FLJ22167, hypothetical protein FLJ22167, PRO1886, TMEM231, Transmembrane protein 231

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive IHC detected inhuman pancreas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inMDCK cells

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

23731-1-AP targets TMEM231 in IHC, IF/ICC, ELISA applications and shows reactivity with human, canine samples.

经测试应用 IHC, IF/ICC, ELISA Application Description
经测试反应性 human, canine
免疫原 TMEM231 fusion protein Ag20669 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 hypothetical protein FLJ22167
别名 ALYE870, FLJ22167, hypothetical protein FLJ22167, PRO1886, TMEM231, Transmembrane protein 231
计算分子量 345 aa, 39 kDa
GenBank蛋白编号BC010609
基因名称 TMEM231
Gene ID (NCBI) 79583
RRIDAB_2879312
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H6L2
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Transmembrane protein 231 (TMEM231) encodes a 36 kDa two-pass transmembrane protein that is part of the B9 complex and localizes to the base of the ciliary axoneme at the TZ. TMEM231 was first identified as a causative gene for MKS and participates in the formation of the diffusion barrier between the cilia and plasma membrane (PMID: 34912761, 37736303). Tmem231 mutant mice have developmental defects reminiscent of MKS patients, including corticomedullary kidney cysts, polydactyly and hepatic ductal plate malformation (PMID: 25869670).

实验方案

Product Specific Protocols
IHC protocol for TMEM231 antibody 23731-1-APDownload protocol
IF protocol for TMEM231 antibody 23731-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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