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验证数据展示

  • IHC staining of mouse skeletal muscle using 31625-1-AP (same clone as 31625-1-PBS)

    IHC staining of mouse skeletal muscle using 31625-1-AP (same clone as 31625-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 31625-1-AP (TMEM164 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31625-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 31625-1-AP (same clone as 31625-1-PBS)

    IF Staining of U2OS using 31625-1-AP (same clone as 31625-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using TMEM164 antibody (31625-1-AP) at dilution of 1:400 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 31625-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse skeletal muscle using 31625-1-AP (same clone as 31625-1-PBS)

    IHC staining of mouse skeletal muscle using 31625-1-AP (same clone as 31625-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 31625-1-AP (TMEM164 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31625-1-PBS in a different storage buffer formulation.

TMEM164 Polyclonal antibody, PBS Only

TMEM164 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 31625-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IF/ICC, Indirect ELISA

别名

bB360B22.3, transmembrane protein 164

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

31625-1-PBS targets TMEM164 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag34317

Product name: Recombinant human TMEM164 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-38 aa of BC085605

Sequence: MSRYSYQSLLDWLYGGVDPSFAGNGGPDCAAFLSWQQR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 transmembrane protein 164
别名 bB360B22.3, transmembrane protein 164
GenBank蛋白编号BC085605
基因名称 TMEM164
Gene ID (NCBI) 84187
RRIDAB_3742456
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ5U3C3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TMEM164 (Transmembrane Protein 164) is a membrane protein with significant roles in various biological processes, including lipid metabolism, neuroprotection, and cancer regulation. In non-small cell lung cancer (NSCLC), TMEM164 promotes ferroptosis by mediating autophagy, leading to the degradation of ferritin, GPX4, and lipid droplets, which facilitates iron accumulation and lipid peroxidation (PMID: 39798196). In neurodegenerative diseases, TMEM164 overexpression via gene therapy shows promise in reducing neurotoxic reactive astrocyte activation and alleviating disease symptoms (PMID: 37679556).

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