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验证数据展示

  • FC experiment of mouse peritoneal macrophages using 98401-1-RR (same clone as 98401-1-PBS)

    FC experiment of mouse peritoneal macrophages using 98401-1-RR (same clone as 98401-1-PBS)

    1x10^6 mouse peritoneal macrophages were surface stained with 0.25 ug Anti-Mouse TIM4 Rabbit RecAb (98401-1-RR, Clone: 242616C10) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were co-stained with CoraLite® Plus 647 Anti-Mouse F4/80. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98401-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse peritoneal macrophages using 98401-1-RR (same clone as 98401-1-PBS)

    FC experiment of mouse peritoneal macrophages using 98401-1-RR (same clone as 98401-1-PBS)

    1x10^6 mouse peritoneal macrophages were surface stained with 0.25 ug Anti-Mouse TIM4 Rabbit RecAb (98401-1-RR, Clone: 242616C10) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98401-1-PBS in a different storage buffer formulation.

Anti-Mouse TIM4 Rabbit Recombinant Antibody, PBS Only

TIM4 Uni-rAb® Recombinant Antibody for FC
Cat No. 98401-1-PBS

产品说明书

CloneNo. 242616C10

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

SMUCKLER, Spleen, mucin-containing, knockout of lymphotoxin protein, T-cell immunoglobulin and mucin domain-containing protein 4, T-cell immunoglobulin mucin receptor 4, T-cell membrane protein 4

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98401-1-PBS targets TIM4 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原

CatNo: Eg3307

Product name: Recombinant Mouse TIM4 protein (rFc Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 23-279 aa of NM_178759

Sequence: ASEDTIIGFLGQPVTLPCHYLSWSQSRNSMCWGKGSCPNSKCNAELLRTDGTRIISRKSTKYTLLGKVQFGEVSLTISNTNRGDSGVYCCRIEVPGWFNDVKKNVRLELRRATTTKKPTTTTRPTTTPYVTTTTPELLPTTVMTTSVLPTTTPPQTLATTAFSTAVTTCPSTTPGSFSQETTKGSAFTTESETLPASNHSQRSMMTISTDIAVLRPTGSNPGILPSTSQLTTQKTTLTTSESLQKTTKSHQINSRQT

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 T-cell immunoglobulin and mucin domain containing 4
别名 SMUCKLER, Spleen, mucin-containing, knockout of lymphotoxin protein, T-cell immunoglobulin and mucin domain-containing protein 4, T-cell immunoglobulin mucin receptor 4, T-cell membrane protein 4
计算分子量 38 kDa
GenBank蛋白编号NM_178759
基因名称 TIM4
Gene ID (NCBI) 276891
RRIDAB_3746044
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ6U7R4
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

T cell immunoglobulin mucin 4 (TIM4) is a macrophage receptor for phosphatidylserine (PtdSer) on apoptotic cells. It is evidenced that TIM4 as phosphatidylserine (PS) receptor is capable of maintaining peritoneal macrophages' homeostatic function and regulating adaptive immunity based on the alteration of Ag-particular T cells' clearance. It is noteworthy that TIM4's dysregulating process was identified under several autoimmune states, in particular inside immune cells. In addition, TIM4 was identified to be over-expressed in Systemic lupus erythematosus (SLE) cases.

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