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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of HeLa using 85859-5-RR (same clone as 85859-5-PBS)

    WB analysis of HeLa using 85859-5-RR (same clone as 85859-5-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 85859-5-RR (TGFB1I1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85859-5-PBS in a different storage buffer formulation.

  • WB analysis of SKOV-3 using 85859-5-RR (same clone as 85859-5-PBS)

    WB analysis of SKOV-3 using 85859-5-RR (same clone as 85859-5-PBS)

    SKOV-3 cells were subjected to SDS PAGE followed by western blot with 85859-5-RR (TGFB1I1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85859-5-PBS in a different storage buffer formulation.

  • WB analysis of rat colon using 85859-5-RR (same clone as 85859-5-PBS)

    WB analysis of rat colon using 85859-5-RR (same clone as 85859-5-PBS)

    rat colon tissue were subjected to SDS PAGE followed by western blot with 85859-5-RR (TGFB1I1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85859-5-PBS in a different storage buffer formulation.

TGFB1I1 Recombinant antibody, PBS Only

TGFB1I1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85859-5-PBS

产品说明书

CloneNo. 250139E8

宿主/亚型

Rabbit / IgG

种属反应性

human, rat

应用

WB, Indirect ELISA

别名

HIC5, Androgen receptor-associated protein of 55 kDa, ARA55, Hic-5, Hydrogen peroxide-inducible clone 5 protein

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TGFB1I1/HIC5 Ready-To-Use IHC Kit. TGFB1I1/HIC5 primary antibody included.

产品信息

85859-5-PBS targets TGFB1I1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, rat
免疫原 TGFB1I1 fusion protein Ag0868 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 transforming growth factor beta 1 induced transcript 1
别名 HIC5, Androgen receptor-associated protein of 55 kDa, ARA55, Hic-5, Hydrogen peroxide-inducible clone 5 protein
计算分子量 48 kDa
观测分子量48-50 kDa
GenBank蛋白编号BC001830
基因名称 HIC5
Gene ID (NCBI) 7041
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO43294
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HIC5 (Hydrogen Peroxide-Inducible Clone 5), also known as TGFB1I1, ARA55, or TSC-5. It was first identified in 1994 as a gene induced by transforming growth factor-β (TGF-β) or hydrogen peroxide (PMID: 36222304). HIC5 is a member of the Paxillin protein family and functions as a molecular adapter, delivering signals when the cellular adhesion environment changes. Given its role in cancer and fibrotic diseases, HIC5 is a potential therapeutic target. For example, targeting HIC5 or the GR tau2 region could modulate the set of genes regulated by GR, providing opportunities for intervention (PMID: 24591583).