验证数据展示
产品信息
85129-5-PBS targets TCL1A in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | TCL1A fusion protein Ag0786 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | T-cell leukemia/lymphoma 1A |
别名 | TCL1, T-cell leukemia/lymphoma protein 1A, Oncogene TCL-1, 242623A9 |
计算分子量 | 13 kDa |
观测分子量 | 15 kDa |
GenBank蛋白编号 | BC005831 |
基因名称 | TCL1A |
Gene ID (NCBI) | 8115 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P56279 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TCL1A, also named as TCL1 and p14 TCL1, enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. TCL1A immunodetection is an independent marker of adverse outcome that could be used in routine settings for the management of DLCL patients. TCL1A expression is correlated with shorter time to treatment in chronic lymphocytic leukemia cases and shorter lymphoma-specific survival in mantle cell lymphoma series. It is a potential therapeutic target.