验证数据展示
产品信息
67371-1-PBS targets TBXAS1 in WB, IHC, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse, pig samples.
| 经测试应用 | WB, IHC, FC (Intra), Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, pig |
| 免疫原 |
CatNo: Ag29177 Product name: Recombinant human TBXAS1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 178-466 aa of BC014117 Sequence: NKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | thromboxane A synthase 1 (platelet) |
| 别名 | 1F6G6, CYP5, CYP5A1, EC:4.2.1.152, EC:5.3.99.5 |
| 计算分子量 | 60 kDa |
| 观测分子量 | 52 kDa |
| GenBank蛋白编号 | BC014117 |
| 基因名称 | TBXAS1 |
| Gene ID (NCBI) | 6916 |
| RRID | AB_2918487 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P24557 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TBXAS1 catalyzes the conversion of the prostaglandin endoperoxide into thromboxane A2 as a potent vasoconstrictor and inducer of platelet aggregation.It was identified as novel airway fibroblast-specific markers with integrin-8 (ITGA8) (PMID:20435685). It was observed in the epithelium.It is a monomer with the molecular weight of 60 KDa. It also has two variants with 60.5 kDa and 52.3 kDa (PMID:1730669). It also reavels a molecular weight of 55 kDa in humen uterus (PMID:1386258).







