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验证数据展示

  • WB analysis using 84990-4-RR (same clone as 84990-4-PBS)

    WB analysis using 84990-4-RR (same clone as 84990-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84990-4-RR (TBC1D5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84990-4-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 84990-4-RR (same clone as 84990-4-PBS)

    IF Staining of A431 using 84990-4-RR (same clone as 84990-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using TBC1D5 antibody (84990-4-RR, Clone: 242534B8 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84990-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84990-4-RR

    Affinity and Kinetic Characterization of 84990-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84990-4-RR against Human TBC1D5 were performed. The affinity constant is 3.28 nM.

TBC1D5 Recombinant monoclonal antibody, PBS Only

TBC1D5 Uni-rAb® Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 84990-4-PBS

产品说明书

CloneNo. 242534B8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

242534B8, KIAA0210, TBC1 domain family member 5, TBC1 domain family, member 5

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy TBC1D5 Ready-To-Use IHC Kit. TBC1D5 primary antibody included.

产品信息

84990-4-PBS targets TBC1D5 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag10991

Product name: Recombinant human TBC1D5 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 445-795 aa of BC013145

Sequence: TNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDDSSKDSGFTIVSPLDI

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 TBC1 domain family, member 5
别名 242534B8, KIAA0210, TBC1 domain family member 5, TBC1 domain family, member 5
计算分子量 795 aa, 89 kDa
观测分子量 89 kDa
GenBank蛋白编号BC013145
基因名称 TBC1D5
Gene ID (NCBI) 9779
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ92609
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TBC1D5, a member of TBC (Tre2/Bub2/Cdc16)1 domain family, is a novel retromer-interacting protein. TBC1D5 is a Rab GTPase-activating proteins (GAPs) proteins that negatively regulates VPS35/29/26 recruitment and causes Rab7 to dissociate from the membrane. TBC1D5 could bridge the endosome and autophagosome via its C-terminal LIR motif, and Rab GAPs are implicated in the reprogramming of the endocytic trafficking events under starvation-induced autophagy. The TBC1D5 protein exists 89 kDa and 91 kDa isoforms.

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