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验证数据展示

  • WB analysis of HEK-293 using 16739-1-AP (same clone as 16739-1-PBS)

    WB analysis of HEK-293 using 16739-1-AP (same clone as 16739-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 16739-1-AP (TASP1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16739-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary using 16739-1-AP (same clone as 16739-1-PBS)

    IHC staining of human ovary using 16739-1-AP (same clone as 16739-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary using 16739-1-AP (TASP1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 16739-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary using 16739-1-AP (same clone as 16739-1-PBS)

    IHC staining of human ovary using 16739-1-AP (same clone as 16739-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary using 16739-1-AP (TASP1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 16739-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 16739-1-AP (same clone as 16739-1-PBS)

    IF Staining of HeLa using 16739-1-AP (same clone as 16739-1-PBS)

    Immunofluorescent analysis of HeLa cells using 16739-1-AP (TASP1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 16739-1-PBS in a different storage buffer formulation.

  • WB analysis using 16739-1-AP (same clone as 16739-1-PBS)

    WB analysis using 16739-1-AP (same clone as 16739-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16739-1-AP (TASP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16739-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

TASP1 Polyclonal antibody, PBS Only

TASP1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 16739-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

C20orf13, EC:3.4.25.-, Taspase 1, Taspase-1, Threonine aspartase 1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

16739-1-PBS targets TASP1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag9918

Product name: Recombinant human TASP1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-420 aa of BC025266

Sequence: MTMEKGMSSGEGLPSRSSQVSAGKITAKELETKQSYKEKRGGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALVELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPNIMTTRFSLAAFKRNKRKLELAERVDTDFMQLKKRRQSSEKENDSGTLDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAHNPYSTAVSTSGCGEHLVRTILARECSHALQAEDAHQALLETMQNKFISSPFLASEDGVLGGVIVLRSCRCSAEPDSSQNKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 taspase, threonine aspartase, 1
别名 C20orf13, EC:3.4.25.-, Taspase 1, Taspase-1, Threonine aspartase 1
计算分子量 420 aa, 44 kDa
观测分子量 50 kDa
GenBank蛋白编号BC025266
基因名称 TASP1
Gene ID (NCBI) 55617
RRIDAB_2201218
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H6P5
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Threonine aspartase 1 (TASP1), a particularly conserved protease that cleaves mixed lineage leukemia 1 (MLL), regulates the expression of homeotic genes and is involved in the occurrence of cancer. TASP1 drives cell cycle progression and coordinates cell proliferation and apoptosis (PMID: 33767369). Aberrant expression of TASP1 has been found in numerous liquid and solid malignancies, including leukaemia, breast cancer, lung cancer, head and neck cancer, brain cancer, colon cancer, glioblastoma and melanoma. TASP1 plays a key role in cancer cell proliferation and apoptosis and can inhibit tumor growth after knockout (PMID: 32071545, 34012990).

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