验证数据展示
产品信息
67451-1-PBS targets TAOK3 in WB, IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, IF/ICC, IF-P, ELISA Application Description | 
| 经测试反应性 | human, mouse | 
| 免疫原 | 
                                             CatNo: Ag29146 Product name: Recombinant human TAOK3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 366-430 aa of BC002756 Sequence: SMQEVMDESSSELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYR 种属同源性预测 | 
                                    
| 宿主/亚型 | Mouse / IgG1 | 
| 抗体类别 | Monoclonal | 
| 产品类型 | Antibody | 
| 全称 | TAO kinase 3 | 
| 别名 | JIK, 1A5A9, CTCL-associated antigen HD-CL-09, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, Dendritic cell-derived protein kinase | 
| 计算分子量 | 105 kDa | 
| 观测分子量 | 100-105 kDa | 
| GenBank蛋白编号 | BC002756 | 
| 基因名称 | TAOK3 | 
| Gene ID (NCBI) | 51347 | 
| RRID | AB_2882685 | 
| 偶联类型 | Unconjugated | 
| 形式 | Liquid | 
| 纯化方式 | Protein A purification | 
| UNIPROT ID | Q9H2K8 | 
| 储存缓冲液 | PBS only, pH 7.3. | 
| 储存条件 | Store at -80°C.  The product is shipped with ice packs. Upon receipt, store it immediately at -80°C  | 
背景介绍
TAOK3(Serine/threonine-protein kinase TAO3) is also named as DPK, JIK, KDS, MAP3K18 and belongs to the STE Ser/Thr protein kinase family. It acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, it is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. And this protein can be autophosphorylated(PMID:20949042).










