验证数据展示
经过测试的应用
| Positive WB detected in | Raji cells, Jurkat cells |
| Positive IP detected in | Raji cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 2 publications below |
产品信息
55317-1-AP targets TAL1 in WB, IP, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IP, ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, zebrafish |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | T-cell acute lymphocytic leukemia 1 |
| 别名 | bHLHa17, SCL, Stem cell protein, tal 1, TAL1, TCL5 |
| 计算分子量 | 34 kDa |
| 观测分子量 | 40-44 kDa |
| GenBank蛋白编号 | NM_003189 |
| 基因名称 | TAL1 |
| Gene ID (NCBI) | 6886 |
| RRID | AB_2881306 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P17542 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
T-cell acute lymphocytic leukemia protein 1 (TAL1) also named Stem cell protein,T-cell leukemia/lymphoma protein 5.It is specifically expressed in leukemic stem cell,implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation, serving as a positive regulator of erythroid differentiation. The 38kd, 44kd bands recognized by antibody are the phosphorylated forms of TAL1 and it's isoforms.
实验方案
| Product Specific Protocols | |
|---|---|
| IP protocol for TAL1 antibody 55317-1-AP | Download protocol |
| WB protocol for TAL1 antibody 55317-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Pharmaceuticals (Basel) Caulis Polygoni Multiflori Accelerates Megakaryopoiesis and Thrombopoiesis via Activating PI3K/Akt and MEK/ERK Signaling Pathways | ||
Development BF170 hydrochloride enhances the emergence of hematopoietic stem and progenitor cells | ||
Nat Immunol Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR-RUNX1 |
