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验证数据展示

  • IHC staining of mouse heart using 20467-1-AP (same clone as 20467-1-PBS)

    IHC staining of mouse heart using 20467-1-AP (same clone as 20467-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 20467-1-AP (C12orf39 antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20467-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 20467-1-AP (same clone as 20467-1-PBS)

    IHC staining of mouse heart using 20467-1-AP (same clone as 20467-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 20467-1-AP (C12orf39 antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20467-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 20467-1-AP (same clone as 20467-1-PBS)

    IHC staining of human kidney using 20467-1-AP (same clone as 20467-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20467-1-AP (Spexin antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20467-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 20467-1-AP (same clone as 20467-1-PBS)

    IHC staining of human kidney using 20467-1-AP (same clone as 20467-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20467-1-AP (Spexin antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20467-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse heart using 20467-1-AP (same clone as 20467-1-PBS)

    IF Staining of mouse heart using 20467-1-AP (same clone as 20467-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse heart tissue using C12orf39 antibody (20467-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20467-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse liver using 20467-1-AP (same clone as 20467-1-PBS)

    IF Staining of mouse liver using 20467-1-AP (same clone as 20467-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse liver tissue using Spexin antibody (20467-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20467-1-PBS in a different storage buffer formulation.

Spexin Polyclonal antibody, PBS Only

Spexin Polyclonal Antibody for IHC, IF-P, Indirect ELISA
Cat No. 20467-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IF-P, Indirect ELISA

别名

C12orf39, Neuropeptide Q, Spexin hormone, Spexin-1, Spexin-2

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

20467-1-PBS targets Spexin in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag14304

Product name: Recombinant human C12orf39 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-116 aa of BC004336

Sequence: MKGLRSLAATTLALFLVFVFLGNSSCAPQRLLERRNWTPQAMLYLKGAQGRRFISDQSRRKDLSDRPLPERRSPNPQLLTIPEAATILLASLQKSPEDEEKNFDQTRFLEDSLLNW

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromosome 12 open reading frame 39
别名 C12orf39, Neuropeptide Q, Spexin hormone, Spexin-1, Spexin-2
计算分子量 116 aa, 13 kDa
GenBank蛋白编号BC004336
基因名称 C12orf39
Gene ID (NCBI) 80763
RRIDAB_3741996
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BT56
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Spexin (SPX), also known as neuropeptide Q, is a novel and highly conserved neuroendocrine peptide discovered through bioinformatics. Spexin and its receptors (primarily galanin receptor types 2 and 3) are widely expressed throughout the body, including the central nervous system, gastrointestinal tract, adipose tissue, kidneys, and cardiovascular system. Research indicates that Spexin is a multifunctional regulatory peptide, with its most central role being in energy homeostasis and metabolic regulation. It functions to suppress appetite, reduce body weight, and improve insulin resistance and glucose metabolism, making it a potential biomarker and therapeutic target for metabolic diseases such as obesity and type 2 diabetes. Additionally, Spexin is involved in regulating various physiological and pathological processes, including pain perception, anxiety- and depression-like behaviors, cardiovascular function, and reproductive activities.

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