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验证数据展示

  • WB analysis using 21245-1-AP (same clone as 21245-1-PBS)

    WB analysis using 21245-1-AP (same clone as 21245-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21245-1-AP (SYT2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse cerebellum using 21245-1-AP (same clone as 21245-1-PBS)

    IF Staining of mouse cerebellum using 21245-1-AP (same clone as 21245-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse cerebellum tissue using SYT2 antibody (21245-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse cerebellum using 21245-1-AP (same clone as 21245-1-PBS)

    IF Staining of mouse cerebellum using 21245-1-AP (same clone as 21245-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse cerebellum tissue using SYT2 antibody (21245-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

SYT2 Polyclonal antibody, PBS Only

SYT2 Polyclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 21245-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF-P, Indirect ELISA

别名

Synaptotagmin II, Synaptotagmin-2, SytII

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

21245-1-PBS targets SYT2 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag15744

Product name: Recombinant human SYT2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-60 aa of BC100815

Sequence: MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 synaptotagmin II
别名 Synaptotagmin II, Synaptotagmin-2, SytII
计算分子量 419 aa, 47 kDa
观测分子量70 kDa
GenBank蛋白编号BC100815
基因名称 SYT2
Gene ID (NCBI) 127833
RRIDAB_3085646
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8N9I0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SYT2 (Synaptotagmin-2) a synaptic vesicle membrane protein, functions as a calcium sensor in vesicular trafficking and exocytosis. SYT2 is also plays a role in dendrite formation by melanocytes (PMID: 23999003). Mutations in SYT2 are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. SYT2 mutations cause a complex presynaptic congenital myasthenic syndrome (PMID: 26519543).

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