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Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis using 61024-1-Ig (same clone as 61024-1-PBS)

    WB analysis using 61024-1-Ig (same clone as 61024-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 61024-1-Ig (STAU1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 61024-1-PBS in a different storage buffer formulation.

  • WB analysis of rabbit liver using 61024-1-Ig (same clone as 61024-1-PBS)

    WB analysis of rabbit liver using 61024-1-Ig (same clone as 61024-1-PBS)

    rabbit liver tissue were subjected to SDS PAGE followed by western blot with 61024-1-Ig (STAU1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 61024-1-PBS in a different storage buffer formulation.

STAU1 Monoclonal antibody, PBS Only

STAU1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 61024-1-PBS

产品说明书

CloneNo. 1H1D7

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat, rabbit

应用

WB, Indirect ELISA

别名

Double-stranded RNA-binding protein Staufen homolog 1, STAU

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy STAU1 Ready-To-Use IHC Kit. STAU1 primary antibody included.

产品信息

61024-1-PBS targets STAU1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, rabbit samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat, rabbit
免疫原

CatNo: Ag5573

Product name: Recombinant human STAU1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 227-577 aa of BC050432

Sequence: GEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 staufen, RNA binding protein, homolog 1 (Drosophila)
别名 Double-stranded RNA-binding protein Staufen homolog 1, STAU
计算分子量 63 kDa
观测分子量55-65 kDa
GenBank蛋白编号BC050432
基因名称 STAU1
Gene ID (NCBI) 6780
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDO95793
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Staufen1 (STAU1)-mediated mRNA decay (SMD) degrades translationally active mRNAs that bind the double-stranded (ds)RNA binding protein STAU1 within their 3'-untranslated regions (3'UTRs) [PMID:21307942]. STAU1 can binds to stem structures and protect Dvl2 mRNA from degradation by associating with the secondary structure in the U1 region which is located at 5′ position of second U stretch in the U2 region [PMID:17510634]. It has a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.

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