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SNX2 Polyclonal antibody, PBS Only

SNX2 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 11737-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

Sorting nexin-2, Transformation-related gene 9 protein, TRG9, TRG-9

缓冲液配方:  PBS Only
偶联物:  Unconjugated
规格价格库存


产品信息

11737-1-PBS targets SNX2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag2259

Product name: Recombinant human SNX2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 171-520 aa of BC003382

Sequence: SMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sorting nexin 2
别名 Sorting nexin-2, Transformation-related gene 9 protein, TRG9, TRG-9
计算分子量 519 aa, 58 kDa
观测分子量~70 kda
GenBank蛋白编号BC003382
基因名称 SNX2
Gene ID (NCBI) 6643
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO60749
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Sorting nexin 2 (SNX2) belongs to the sorting nexin family, characterized by the presence of a phox (PX) domain that binds phosphoinositides and mediates intracellular trafficking. It regulates the cell-surface expression and degradation of epidermal growth factor receptor (EGFR) through endosomal sorting (PMID: 14978220). SNX2 also participates in retrograde transport from endosomes to the trans-Golgi network and maintains cellular homeostasis (PMID: 38033809).

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