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验证数据展示

  • WB analysis using 13131-1-AP (same clone as 13131-1-PBS)

    WB analysis using 13131-1-AP (same clone as 13131-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13131-1-AP (SNTA1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13131-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 13131-1-AP (same clone as 13131-1-PBS)

    IHC staining of mouse heart using 13131-1-AP (same clone as 13131-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 13131-1-AP (SNTA1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13131-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 13131-1-AP (same clone as 13131-1-PBS)

    IHC staining of mouse heart using 13131-1-AP (same clone as 13131-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 13131-1-AP (SNTA1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13131-1-PBS in a different storage buffer formulation.

SNTA1 Polyclonal antibody, PBS Only

SNTA1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 13131-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

13131-1-PBS targets SNTA1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag3820

Product name: Recombinant human SNTA1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 156-505 aa of BC026215

Sequence: KKTGKEVVLEVKYMKDVSPYFKNSTGGTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEASARSWATAIQAQVNTLTPRVKDELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYLSLPETREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAWTRQLVDGCHRAAEGVQEVSTACTWNGRPCSLSVHIDKGFTLWAAEPGAARAVLLRQPFEKLQMSSDDGASLLFLDFGGAEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLLA

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
别名
计算分子量 505 aa, 54 kDa
观测分子量 54 kDa
GenBank蛋白编号BC026215
基因名称 SNTA1
Gene ID (NCBI) 6640
RRIDAB_3085408
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ13424
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SNTA1, also known as Syntrophin 1, SNT1, is cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. SNTA1 is a signal-transducing adaptor protein and serves as a scaffold for various signaling molecules. Alpha-1 syntrophin contains a PDZ domain, two Pleckstrin homology domains, and a 'syntrophin unique' domain. SNTA1 is the high expression in skeletal muscle and heart (PMID: 8576247, 8612778,). The PDZ domain of SNTA1 has been reported to bind to the C-terminal domain of murine cardiac voltage-gated sodium channels (SkM2) causing altering ion channel activity leading to Long QT syndrome(PMID 19684871, 19862833).

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