验证数据展示
产品信息
67979-1-PBS targets SMARCB1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | SMARCB1 fusion protein Ag28911 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
别名 | INI1, hSNFS, hSNF5, BRG1-associated factor 47, BAF47 |
计算分子量 | 44 kDa |
观测分子量 | 40-45 kDa |
GenBank蛋白编号 | NM_003073 |
基因名称 | SMARCB1 |
Gene ID (NCBI) | 6598 |
RRID | AB_2918728 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q12824 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.