- Featured Product
- KD/KO Validated
SLMAP Polyclonal antibody
SLMAP Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | mouse heart tissue, A431 cells, mouse skeletal muscle tissue |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
产品信息
The immunogen of 25220-1-AP is SLMAP Fusion Protein expressed in E. coli.
| Tested Applications | WB, ELISA |
| Cited Applications | WB |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Immunogen | SLMAP fusion protein Ag18162 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | sarcolemma associated protein |
| Synonyms | KIAA1601, sarcolemma associated protein, Sarcolemmal associated protein, SLAP, SLMAP |
| Calculated Molecular Weight | 828 aa, 95 kDa |
| Observed Molecular Weight | 35 kDa, 45 kDa, 63-66 kDa, 83-91 kDa |
| GenBank Accession Number | BC115701 |
| Gene Symbol | SLMAP |
| Gene ID (NCBI) | 7871 |
| RRID | AB_2879968 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q14BN4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35-kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91-kDa isoform is ubiquitous. This antibody recognizes all of these isoforms in mouse heart lysate. (21785580, 22180652)
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for SLMAP antibody 25220-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Thorac Cancer Tumor suppressor effect of an antibody on xenotransplanted sarcomatoid mesothelioma cells
|
