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验证数据展示

  • WB analysis using 19743-1-AP (same clone as 19743-1-PBS)

    WB analysis using 19743-1-AP (same clone as 19743-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 19743-1-AP (SLK antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19743-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 19743-1-AP (same clone as 19743-1-PBS)

    IF Staining of HepG2 using 19743-1-AP (same clone as 19743-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using SLK antibody (19743-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 19743-1-PBS in a different storage buffer formulation.

SLK Polyclonal antibody, PBS Only

SLK Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 19743-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF/ICC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy SLK Ready-To-Use IHC Kit. SLK primary antibody included.

产品信息

19743-1-PBS targets SLK in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 STE20-like kinase (yeast)
别名
计算分子量 143 kDa
观测分子量 143-160 kDa, 210-220 kDa
GenBank蛋白编号NM_014720
基因名称 SLK
Gene ID (NCBI) 9748
RRIDAB_10644278
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H2G2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLK, also named as KIAA0204 and STK2, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. SLK plays an important role in cell proliferation and cytoskeletal remodeling. In fibroblasts, SLK has been shown to respond to FAK/Src signaling and regulate focal adhesion turnover through Paxillin phosphorylation. Full-length SLK (~220 kDa) has also been shown to be essential for embryonic development. In myoblasts, the overexpression of a dominant negative SLK is sufficient to block myoblast fusion. (PMID: 28153048, PMID: 25882817, PMID: 23815977)

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