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验证数据展示

  • WB analysis using 29372-1-AP (same clone as 29372-1-PBS)

    WB analysis using 29372-1-AP (same clone as 29372-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29372-1-AP (SLC6A19 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29372-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 29372-1-AP (same clone as 29372-1-PBS)

    IHC staining of human small intestine using 29372-1-AP (same clone as 29372-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 29372-1-AP (SLC6A19 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29372-1-PBS in a different storage buffer formulation.

SLC6A19 Polyclonal antibody, PBS Only

SLC6A19 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 29372-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

B0AT1, HND, Sodium-dependent neutral amino acid transporter B(0)AT1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

29372-1-PBS targets SLC6A19 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag31076

Product name: Recombinant human SLC6A19 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 142-192 aa of BC148801

Sequence: NSFQEPLPWSDCPLNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 6 (neutral amino acid transporter), member 19
别名 B0AT1, HND, Sodium-dependent neutral amino acid transporter B(0)AT1
计算分子量 634 aa, 71 kDa
观测分子量70 kDa
GenBank蛋白编号BC148801
基因名称 SLC6A19
Gene ID (NCBI) 340024
RRIDAB_2918286
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ695T7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC6A19, also named as B0AT1, encodes system B(0) transmembrane protein that mediates epithelial resorption of neutral amino acids across the apical membrane in kidney and intestine (PubMed: 15044460). The protein contains 634 amino acids and has 12 predicted transmembrane regions with highly expression in human kidney and small intestine and minimal in pancreas (PubMed: 15286787). The expression of SLC6A19 in intestinal cells depends on angiotensin converting enzyme 2 which is the cellular receptor for SARS-CoV-2 (PubMed: 32132184). Mutations in SLC6A19 cause Hartnup disease (PMID: 15286787, PMID: 15286788).

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