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验证数据展示

  • IHC staining of human small intestine using 30396-1-AP (same clone as 30396-1-PBS)

    IHC staining of human small intestine using 30396-1-AP (same clone as 30396-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 30396-1-AP (SLC52A2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30396-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 30396-1-AP (same clone as 30396-1-PBS)

    IHC staining of human small intestine using 30396-1-AP (same clone as 30396-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 30396-1-AP (SLC52A2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30396-1-PBS in a different storage buffer formulation.

SLC52A2 Polyclonal antibody, PBS Only

SLC52A2 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 30396-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, Indirect ELISA

别名

GPCR, GPCR41, GPR172A, PAR1, RFT3

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

30396-1-PBS targets SLC52A2 in IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag33252

Product name: Recombinant human GPR172A protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 217-276 aa of BC002917

Sequence: LLPPPPSVPTGELGSGLQVGAPGAEEEVEESSPLQEPPSQAAGTTPGPDPKAYQLLSARS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 Solute carrier family 52, riboflavin transporter, member 2
别名 GPCR, GPCR41, GPR172A, PAR1, RFT3
计算分子量 46 kDa
GenBank蛋白编号BC002917
基因名称 SLC52A2
Gene ID (NCBI) 79581
RRIDAB_3742338
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9HAB3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC52A2 (Also known as RFVT2, RFT3) is a membrane protein that belongs to the riboflavin transporter family. SLC52A2 is a transmembrane protein that mediates cellular uptake of riboflavin. Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption (PubMed:20463145). Mutations in SLC52A2 have been associated with Brown-Vialetto-Van Laere syndrome 2 (BVVLS2) - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia (PMID: 22864630, 23243084).

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