验证数据展示
产品信息
87846-1-PBS targets SLC28A2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 |
| 别名 | CNT 2, CNT2, hCNT2, HsT17153, Sodium/purine nucleoside co-transporter |
| 计算分子量 | 658 aa, 72 kDa |
| 观测分子量 | 65-71 kDa |
| GenBank蛋白编号 | BC093737 |
| 基因名称 | SLC28A2 |
| Gene ID (NCBI) | 9153 |
| RRID | AB_3745785 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O43868 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Solute carrier family 28 member 2 (SLC28A2), also called concentrative nucleoside transporter 2 (CNT2), is found mainly in the gastrointestinal tract and kidney (PMID: 10087507). The SLC28A2 gene, which is mapped to chromosome 15q21.1 in humans, encodes a sodium/nucleoside symporter preferentially located at the apical side of polarized epithelia, thereby mediating the unidirectional uptake of sodium ions coupled with nucleosides (PMID: 29928232). SLC28A2, a sodium-dependent and purine-selective transporter, has been reported to translocate antiviral purine analogs (PMID: 36244249). SLC28A2 gene, is expressed in luminal membrane of intestine and mediates efficient transport of dietary purine nucleosides and nucleoside analog ribavirin (PMID: 30679935).
