验证数据展示
产品信息
87551-1-PBS targets SLC25A29 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag24662 Product name: Recombinant human SLC25A29 protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 1-146 aa of BC132966 Sequence: MGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDV 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | solute carrier family 25, member 29 |
| 别名 | C14orf69, CACT-like, Carnitine/acylcarnitine translocase-like, Mitochondrial basic amino acids transporter, Mitochondrial carnitine/acylcarnitine carrier protein CACL |
| 计算分子量 | 303 aa, 32 kDa |
| 观测分子量 | 32 kDa |
| GenBank蛋白编号 | BC132966 |
| 基因名称 | SLC25A29 |
| Gene ID (NCBI) | 123096 |
| RRID | AB_3745615 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q8N8R3 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLC25A29 is a mitochondrial transporter belonging to the SLC25 superfamily, which facilitates the exchange of metabolites across the inner mitochondrial membrane. Initially reported as a carnitine/acylcarnitine-like carrier, it is now recognized as a key amino acid transporter, particularly for arginine and lysine, contributing to mitochondrial protein synthesis and amino acid degradation. SLC25A29 is primarily expressed in the heart, brain, liver, and kidneys and is associated with metabolic disorders and vascular diseases. Its expression is regulated by histone lactose modification and is associated with conditions such as lung adenocarcinoma and diabetic retinopathy.(PMID: 24652292; 37775731;29459713; 40244673)
