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验证数据展示

  • IHC staining of human colon cancer using 10789-1-AP (same clone as 10789-1-PBS)

    IHC staining of human colon cancer using 10789-1-AP (same clone as 10789-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10789-1-AP (SLC25A13 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10789-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 10789-1-AP (same clone as 10789-1-PBS)

    IHC staining of human colon cancer using 10789-1-AP (same clone as 10789-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10789-1-AP (SLC25A13 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10789-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 10789-1-AP (same clone as 10789-1-PBS)

    IHC staining of human lung cancer using 10789-1-AP (same clone as 10789-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 10789-1-AP (SLC25A13 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10789-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 10789-1-AP (same clone as 10789-1-PBS)

    IF Staining of U2OS using 10789-1-AP (same clone as 10789-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using SLC25A13 antibody (10789-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-phalloidin (red). This data was developed using the same antibody clone with 10789-1-PBS in a different storage buffer formulation.

SLC25A13 Polyclonal antibody, PBS Only

SLC25A13 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 10789-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, IF/ICC, Indirect ELISA

别名

ARALAR2, ARALAR-related gene 2, Calcium-binding mitochondrial carrier protein Aralar2, Citrin, Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

10789-1-PBS targets SLC25A13 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag1242

Product name: Recombinant human SLC25A13 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 336-675 aa of BC006566

Sequence: SVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWFYIDFGGVKPMGSEPVPKSRINLPAPNPDHVGGYKLAVATFAGIENKFGLYLPLFKPSVSTSKAIGGGP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 25, member 13 (citrin)
别名 ARALAR2, ARALAR-related gene 2, Calcium-binding mitochondrial carrier protein Aralar2, Citrin, Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial
计算分子量 74 kDa
GenBank蛋白编号BC006566
基因名称 SLC25A13
Gene ID (NCBI) 10165
RRIDAB_2189738
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UJS0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC25A13, also known as citrin, has been identified as a mitochondrial aspartate-glutamate carrier protein and may be implicated in metabolic compartmentation. It consists of 675 amino acid residues and harbors four EF-hands and six mitochondrial transmembranous (TM) spanners. Mutations in SLC25A13 gene cause adult-onset type II citrullinemia (CTLN2) and neonatal intrahepatic cholestasis (NICCD). The complete deletion or cleaved SLA25A13 proteins have been reported in patients with SLC25A13 mutation.

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