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验证数据展示

  • WB analysis using 26833-1-AP (same clone as 26833-1-PBS)

    WB analysis using 26833-1-AP (same clone as 26833-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26833-1-AP (SLC22A16 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 26833-1-AP (same clone as 26833-1-PBS)

    IHC staining of human breast cancer using 26833-1-AP (same clone as 26833-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 26833-1-AP (SLC22A16 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

  • IF Staining of THP-1 using 26833-1-AP (same clone as 26833-1-PBS)

    IF Staining of THP-1 using 26833-1-AP (same clone as 26833-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using SLC22A16 antibody (26833-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

SLC22A16 Polyclonal antibody, PBS Only

SLC22A16 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 26833-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

26833-1-PBS targets SLC22A16 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag25270

Product name: Recombinant human SLC22A16 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 48-150 aa of BC047565

Sequence: PHHVCRPPGNVSQVVFHNHSNWSLEDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 22 (organic cation/carnitine transporter), member 16
别名
计算分子量 65 kDa
观测分子量68 kDa
GenBank蛋白编号BC047565
基因名称 SLC22A16
Gene ID (NCBI) 85413
RRIDAB_2923576
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86VW1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC22A16, also named as CT2, FLIPT2, or OCT6, belongs to the major facilitator (TC 2.A.1) superfamily and organic cation transporter (TC 2.A.1.19) family. SLC22A16 encodes an organic zwitterion transporter protein that transports carnitine and some anticancer drugs, including anthracyclines. As a carnitine transporter, SLC22A16 is involved in the regulation of fatty acid oxidation (FAO), which plays an important role also in the metabolic transformation of cancer cells. SLC22A16 expression in cancer cells is associated with increased sensitivity to the cytotoxic effects of doxorubicin. SLC22A16 has 3 isoforms with the molecular mass of 58, 61 and 65 kDa (PMID: 35761855, 35608746).

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