FcZero-rAb™ PE Anti-Human SLAMF7/CD319 Rabbit Recombinant Antibody

SLAMF7/CD319 FcZero-rAbTM Recombinant Antibody for FC
Cat No. PE-FcA98093

产品说明书

CloneNo. 241321F11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

SLAMF7, FOAP-12, CS1, CRACC, CD319

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  PE
规格: 

-/ -


经过测试的应用

Positive FC detected inhuman PBMCs

推荐稀释比

应用推荐稀释比
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

PE-FcA98093 targets SLAMF7/CD319 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 SLAM family member 7
别名 SLAMF7, FOAP-12, CS1, CRACC, CD319
计算分子量 335 aa, 37 kDa
GenBank蛋白编号BC027867
基因名称 SLAMF7
Gene ID (NCBI) 57823
偶联类型 PE Fluorescent Dye
最大激发/发射波长496 nm, 565 nm / 578 nm
形式 Liquid
纯化方式Protein A purification
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Signaling lymphocyte activation molecule (SLAM) family receptors is a group of type I transmembrane receptors belonging to the immunoglobulin superfamily (PMID: 37251372). The SLAM family contains nine members that contain an extracellular segment comprising two or four Ig-like domains (V-like variable and C2-like constant), a transmembrane region and a cytoplasmic tail (PMID: 29662641). They are involved in various physiological and pathological processes, including the regulation of immunological responses and the route of viral entry. SLAMF7, also known as CS1, CRACC or CD319, is expressed on NK cells, CD8+ T lymphocytes, B lymphocytes, and mature dendritic cells (PMID: 28861320). It exerts both activating and inhibitory effects depending on the expression status of SAP or EAT-2. SLAMF7 is overexpressed in multiple myeloma and makes it a target for immunotherapy (PMID: 28861320).

实验方案

Product Specific Protocols
FC protocol for PE SLAMF7/CD319 antibody PE-FcA98093Download protocol
Standard Protocols
Click here to view our Standard Protocols
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