验证数据展示
产品信息
67257-1-PBS targets SIRT5 in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | SIRT5 fusion protein Ag7743 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) |
别名 | FLJ36950, SIR2 like protein 5, SIR2L5, SIRT5 |
计算分子量 | 34 kDa |
观测分子量 | 33 kDa |
GenBank蛋白编号 | BC000126 |
基因名称 | SIRT5 |
Gene ID (NCBI) | 23408 |
RRID | AB_2882530 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9NXA8 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SIRT5, a member fo sirtuin family that is a mitochondrial matrix NAD(+)-dependent deacetylase and mono-ADP-ribosyltransferases. Sirtuins play important role in various cellular processed, such as aging, gene silencing and metabolism. SIRT5 mainly locates in . It is an efficient protein lysine desuccinylase and demalonylase. During prolonged fasting, it can activate CPS1, the committed and regulated enzyme of the urea cycle, and contribute to the regulation of blood ammonia levels.