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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98267-1-RR (same clone as 98267-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98267-1-RR (same clone as 98267-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human SIRP beta 1/CD172b Rabbit Recombinant Antibody (98267-1-RR, Clone: 242115C10) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98267-1-PBS in a different storage buffer formulation.

  • FC experiment of human peripheral blood leukocytes using 98267-1-RR (same clone as 98267-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98267-1-RR (same clone as 98267-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human SIRP beta 1/CD172b Rabbit Recombinant Antibody (98267-1-RR, Clone: 242115C10) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98267-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98267-1-RR

    Affinity and Kinetic Characterization of 98267-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98267-1-RR against Human SIRP beta 1/CD172b were performed. The affinity constant is 22.8 pM.

Anti-Human SIRP beta 1/CD172b Rabbit Recombinant Antibody, PBS Only

SIRP beta 1/CD172b Uni-rAb® Recombinant Antibody for FC
Cat No. 98267-1-PBS

产品说明书

CloneNo. 242115C10

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

SIRP BETA 1, SIRPB1, 242115C10, CD172 antigen-like family member B, CD172b

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98267-1-PBS targets SIRP beta 1/CD172b in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg1668

Product name: Recombinant Human SIRP beta 1/CD172b protein (rFc Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 30-371 aa of NM_006065.5

Sequence: EDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAVRATPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEIAHITLQGDPLRGTANLSEAIRVPPTLEVTQQPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETASTLIENKDGTYNWMSWLLVNTCAHRDDVVLTCQVEHDGQQAVSKSYALEISAHQKEHGSDITHEAALAPTAPL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 signal-regulatory protein beta 1
别名 SIRP BETA 1, SIRPB1, 242115C10, CD172 antigen-like family member B, CD172b
计算分子量43kDa
GenBank蛋白编号NM_006065.5
基因名称 SIRPB1
Gene ID (NCBI) 10326
RRIDAB_3745933
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDO00241-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SIRP beta 1, also known as CD172b, is a member of the signal-regulatory-protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRP family members are cell surface signaling receptors differentially expressed in leukocytes and the central nervous system. SIRP beta 1 interacts with TYROBP/DAP12, a protein-bearing immunoreceptor tyrosine-based activation motif. SIRP beta 1 also participates in the recruitment of tyrosine kinase SYK.

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