SIGMAR1 Recombinant antibody

SIGMAR1 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 85064-1-RR

产品说明书

CloneNo. 242621C6

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

Sigma 1 type opioid receptor, OPRS1, hSigmaR1, Aging-associated gene 8 protein, AAG8

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHEK-293T cells, COLO 320 cells, C2C12 cells, C6 cells, mouse colon tissue, ratcolon tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

85064-1-RR targets SIGMAR1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 SIGMAR1 fusion protein Ag7351 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 sigma non-opioid intracellular receptor 1
别名 Sigma 1 type opioid receptor, OPRS1, hSigmaR1, Aging-associated gene 8 protein, AAG8
计算分子量 25 kDa
观测分子量25 kDa
GenBank蛋白编号BC004899
基因名称 SIGMAR1
Gene ID (NCBI) 10280
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ99720
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SIGMAR1, also named as OPRS1, SRBP, SIG-1R and AAG8, belongs to the ERG2 family. It is an endoplasmic reticulum chaperone that binds a wide variety of ligands, including neurosteroids, psychostimulants, and dextrobenzomorphans. SIGMAR1 is ubiquitously expressed, and is enriched in motor neurons of the brain and spinal cord. It plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. SIGMAR1 plays a role in several other cell functions including proliferation, survival and death. SDS-PAGE and Western blot analysis showed that SIGMAR1 has an apparent molecular mass of 25 kDa. SIGMAR1 has 5 isoforms with MW 21-27kDa and 12kDa.

实验方案

Product Specific Protocols
WB protocol for SIGMAR1 antibody 85064-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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