×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of HEK-293 using 55320-1-AP (same clone as 55320-1-PBS)

    WB analysis of HEK-293 using 55320-1-AP (same clone as 55320-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 55320-1-AP (SH2D5 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55320-1-PBS in a different storage buffer formulation.

  • IHC staining of human cerebellum using 55320-1-AP (same clone as 55320-1-PBS)

    IHC staining of human cerebellum using 55320-1-AP (same clone as 55320-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cerebellum tissue slide using 55320-1-AP (SH2D5 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55320-1-PBS in a different storage buffer formulation.

  • IHC staining of human cerebellum using 55320-1-AP (same clone as 55320-1-PBS)

    IHC staining of human cerebellum using 55320-1-AP (same clone as 55320-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cerebellum tissue slide using 55320-1-AP (SH2D5 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55320-1-PBS in a different storage buffer formulation.

  • IF Staining of HEK-293 using 55320-1-AP (same clone as 55320-1-PBS)

    IF Staining of HEK-293 using 55320-1-AP (same clone as 55320-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HEK-293 cells using SH2D5 antibody (55320-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 55320-1-PBS in a different storage buffer formulation.

SH2D5 Polyclonal antibody, PBS Only

SH2D5 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 55320-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

SH2 domain-containing protein 5, SH2 domain containing 5

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

55320-1-PBS targets SH2D5 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 SH2 domain containing 5
别名 SH2 domain-containing protein 5, SH2 domain containing 5
计算分子量 37 kDa
观测分子量 43-47 kDa
GenBank蛋白编号NM_001103160
基因名称 SH2D5
Gene ID (NCBI) 400745
RRIDAB_2881307
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ6ZV89
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SH2D5, or Src homology 2 domain-containing protein 5, is a mammalian-specific adaptor-like protein that contains an N-terminal phosphotyrosine-binding domain and a C-terminal Src homology 2 (SH2) domain. SH2D5 has been found to interact with the breakpoint cluster region protein, a RacGAP that is also highly expressed in the brain. This interaction occurs between the phosphotyrosine-binding domain of SH2D5 and an NxxF motif located within the N-terminal region of the breakpoint cluster region. Furthermore, SH2D5 has been implicated in the regulation of cell growth in hepatocellular carcinoma cells, where it binds to transketolase (TKT) and promotes the activity of STAT3, a key transcription factor involved in cell proliferation and survival.

||
New chat

Able™

正在加载，请稍候...