验证数据展示
产品信息
24377-1-PBS targets SETD6 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag19485 Product name: Recombinant human SETD6 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 124-473 aa of BC022451 Sequence: PLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANISSEYQSIVLPFMEAHPDLFSLGVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPVMVPAADILNHLANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGSLTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | SET domain containing 6 |
| 别名 | |
| 计算分子量 | 473 aa, 53 kDa |
| 观测分子量 | 53 kDa |
| GenBank蛋白编号 | BC022451 |
| 基因名称 | SETD6 |
| Gene ID (NCBI) | 79918 |
| RRID | AB_2879514 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8TBK2 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SETD6 also named as SET domain containing 6 is a 473 amino-acid protein, which localizes in the Nucleus. The molecular weight of SETD6 is 53kDa. SETD6 consists of 1 SET domain and belongs to the class V-like SAM-binding methyltransferase superfamily. SETD6 as a protein-lysine N-methyltransferase that specifically monomethylates at Lysine 310 of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.
