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验证数据展示

  • WB analysis using 22571-1-AP (same clone as 22571-1-PBS)

    WB analysis using 22571-1-AP (same clone as 22571-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22571-1-AP (SEMA6B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22571-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 22571-1-AP (same clone as 22571-1-PBS)

    IP experiment of mouse brain using 22571-1-AP (same clone as 22571-1-PBS)

    IP result of anti-SEMA6B (IP:22571-1-AP, 4ug; Detection:22571-1-AP 1:1000) with mouse brain tissue lysate 1120 ug. This data was developed using the same antibody clone with 22571-1-PBS in a different storage buffer formulation.

SEMA6B Polyclonal antibody, PBS Only

SEMA6B Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 22571-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IP, Indirect ELISA

别名

SEM SEMA Y, SEMA VIB, Sema Z, SEMAN, Semaphorin 6B

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

22571-1-PBS targets SEMA6B in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag16707

Product name: Recombinant human SEMA6B protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 625-888 aa of BC142617

Sequence: RERRELARRKDKEAILAHGAGEAVLSVSRLGERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSGLLPTPEQTPLPQKRLPTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTPDGRLYAARPGRASHGDFPLTPHASPDRRRVVSAPTGPLDPASAADGLPRPWSPPPTGSLRRPLGPHAPPAATLRRTHTFNSGEARPGDRHRGCHARPGTDLAHLLPYGGADRTAPPVP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
别名 SEM SEMA Y, SEMA VIB, Sema Z, SEMAN, Semaphorin 6B
计算分子量95, 74 kDa
观测分子量70 kDa
GenBank蛋白编号BC142617
基因名称 SEMA6B
Gene ID (NCBI) 10501
RRIDAB_3742073
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen Affinity purified
UNIPROT IDQ9H3T3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Semaphorins (SEMAs) play critical roles in inflammation, angiogenesis, apoptosis, fibrosis, bone remodeling, and cell invasion. SEMA6B, the sixth member of the SEMA family, has shown significant correlations with the stage of liver fibrosis in hepatitis C virus-infected patients. SEMA6B is also involved in inflammatory responses and serves as a biomarker for macrophage-specific genes. Additionally, the level of SEMA6B in circulating monocytes has predictive value for cardiovascular disease. Also, SEMA6B can be a valuable biomarker for diagnosing HBV-ACLF12 (PMID: 39267780).

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