验证数据展示
产品信息
32117-1-PBS targets SBK2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag37233 Product name: Recombinant human SBK2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 185-348 aa of NM_001101401 Sequence: KPENVLVCDPACRRFKLTDFGHTRPRGTLLRLAGPPIPYTAPELCAPPPLPEGLPIQPALDAWALGVLLFCLLTGYFPWDRPLAEADPFYEDFLIWQASGQPRDRPQPWFGLAAAADALLRGLLDPHPRRRSAVIAIREHLGRPWRQREGEAEAVGAVEEEAGQ 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | SH3-binding domain kinase family, member 2 |
| 别名 | Sugen kinase 69 (SgK069), SH3 domain-binding kinase family member 2, SGK069, Serine/threonine-protein kinase SBK2 |
| 计算分子量 | 38 kDa |
| 观测分子量 | 30 kDa |
| GenBank蛋白编号 | NM_001101401 |
| 基因名称 | SBK2 |
| Gene ID (NCBI) | 646643 |
| RRID | AB_3670197 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | P0C263 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SH3 domain binding kinase family member 2 (SBK2, also known as SGK069), is an evolutionarily conserved putative serine/threonine protein kinase that plays a crucial role in cardiomyocyte differentiation, particularly in the formation and maintenance of sarcomeres. It is highly atrium-enriched and is muscle-specific, indicating its specialized function in cardiac muscle cells (PMID: 35587025). SBK2 may be useful for identifying and co-registering tumor borders during surgical resection (PMID: 23730413).

