验证数据展示
产品信息
82923-1-PBS targets S100A16 in WB, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, FC (Intra), Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | S100A16 fusion protein Ag2023 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | S100 calcium binding protein A16 |
别名 | Protein S100-A16, Protein S100 F, Protein S100 A16, Aging-associated gene 13 protein, AAG13 |
计算分子量 | 103 aa, 12 kDa |
观测分子量 | 12 kDa |
GenBank蛋白编号 | BC019099 |
基因名称 | S100A16 |
Gene ID (NCBI) | 140576 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q96FQ6 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
S100A16 is a member of the S100 protein family. S100A16 is expressed in a variety of human tissues. S100A16 expression is especially high in tissues rich in epithelial cells. Functionally, S100A16 has been linked to several aspects of tumorigenesis, for example, cell proliferation, differentiation, migration, invasion, and epithelial-mesenchymal transition (EMT).Accordingly, S100A16 has been suggested to have both tumour-promoting and suppressive roles in human cancers. S100A16-mediated cellular functions are suggested to be mediated by the regulation of various signaling pathways/proteins including EMT-related proteins E-cadherin and Vimentin, PI3K-AKT, p53, MMP1-1, MMP-2, MMP-9, JNK/p38, etc. (PMID: 37509106).