验证数据展示
产品信息
32033-1-PBS targets RSPH1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag36560 Product name: Recombinant human RSPH1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-309 aa of BC101519 Sequence: MSDLGSEELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGKFLNKNPVGPGKYVFDVGCEQHGEYRLTDMERGEEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAPGAESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEGNINSEEEETRQSDLQD 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | radial spoke head 1 homolog (Chlamydomonas) |
| 别名 | Radial Spoke Head Component 1, Radial spoke head 1 homolog, Meichroacidin, Male meiotic metaphase chromosome-associated acidic protein, CT79 |
| 计算分子量 | 309 aa, 35 kDa |
| 观测分子量 | 41 kDa |
| GenBank蛋白编号 | BC101519 |
| 基因名称 | RSPH1 |
| Gene ID (NCBI) | 89765 |
| RRID | AB_3742513 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q8WYR4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RSPH1 (Radial Spoke Head Component 1) encodes a male mid-meiotic chromosome-associated acidic protein involved in the structure and function of cilia and flagella. Pathogenic variants of RSPH1 lead to impaired spermatocyte motility and aberrant flagellar composition, which further contribute to male infertility. In addition to this, mutations in the RSPH1 gene lead to primary ciliary dyskinesia-24 (PCD-24), an autosomal recessive disorder that affects the motor function of cilia and flagella.
