×
Use Able AI chat for product recommendations

验证数据展示

  • IHC staining of mouse brain using 11396-1-AP (same clone as 11396-1-PBS)

    IHC staining of mouse brain using 11396-1-AP (same clone as 11396-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11396-1-AP (RPH3A antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11396-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11396-1-AP (same clone as 11396-1-PBS)

    IHC staining of mouse brain using 11396-1-AP (same clone as 11396-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11396-1-AP (RPH3A antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11396-1-PBS in a different storage buffer formulation.

  • WB analysis of COLO 320 using 11396-1-AP (same clone as 11396-1-PBS)

    WB analysis of COLO 320 using 11396-1-AP (same clone as 11396-1-PBS)

    COLO 320 cells were subjected to SDS PAGE followed by western blot with 11396-1-AP (RPH3A antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11396-1-PBS in a different storage buffer formulation.

  • IF Staining of SH-SY5Y using 11396-1-AP (same clone as 11396-1-PBS)

    IF Staining of SH-SY5Y using 11396-1-AP (same clone as 11396-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using RPH3A antibody (11396-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 11396-1-PBS in a different storage buffer formulation.

RPH3A Polyclonal antibody, PBS Only

RPH3A Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 11396-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

Rabphilin 3A, Rabphilin, KIAA0985, Exophilin-1, Exophilin1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

11396-1-PBS targets RPH3A in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag1956

Product name: Recombinant human RPH3A protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-300 aa of BC017259

Sequence: MTDTVFSNSSNRWMYPSDRPLQSKLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 rabphilin 3A homolog (mouse)
别名 Rabphilin 3A, Rabphilin, KIAA0985, Exophilin-1, Exophilin1
计算分子量 690 aa, 76 kDa
观测分子量 76 kDa
GenBank蛋白编号BC017259
基因名称 RPH3A
Gene ID (NCBI) 22895
RRIDAB_2181145
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y2J0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RAB3A is a small G protein that is thought to act in exocytosis of neurotransmitters and hormones in synaptic neurotransmission and cell-cell communication. RPH3A (RPH3A), a RAB3A effector, is a neuronal C2 domain tandem containing protein that is involved in the neuronal transmitter process. Huntington's disease (HD) is a hereditary neurodegenerative disorder characterized by progressive motor disturbances, cognitive defects and dementia. Level of rabphilin 3A is substantially decreased in synapses of most brain regions in R6/1 transgenic mouse model of HD suggesting a role of RPH3A in impaired synaptic transmission.

||
New chat

Able™

正在加载，请稍候...