验证数据展示
产品信息
21671-1-PBS targets RHBDL3 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag16499 Product name: Recombinant human RHBDL3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-160 aa of BC100975 Sequence: MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCC 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | rhomboid, veinlet-like 3 (Drosophila) |
| 别名 | EC:3.4.21.105, RHBDL4, Rhomboid related protein 3, Rhomboid-related protein 3, VRHO |
| 计算分子量 | 404 aa, 45 kDa |
| 观测分子量 | 40 kDa |
| GenBank蛋白编号 | BC100975 |
| 基因名称 | RHBDL3 |
| Gene ID (NCBI) | 162494 |
| RRID | AB_3742047 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P58872 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RHBDL3 (Rhomboid-related protein 3) is involved in a process known as regulated intramembrane proteolysis (RIP), where proteins are cleaved within the membrane to release functional polypeptides from their membrane anchors. It is expressed in several structures, including the central nervous system, embryo ectoderm, reproductive system, sensory organ, and thymus. RHBDL3 is also a prognostic marker in Glioblastoma multiforme, indicating its potential role in cancer-related pathways. It is expressed in various cell lines, particularly in those related to neuronal function and visual perception, with low cancer specificity.
