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验证数据展示

  • WB analysis using 17703-1-AP (same clone as 17703-1-PBS)

    WB analysis using 17703-1-AP (same clone as 17703-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 17703-1-AP (REV1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17703-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 17703-1-AP (same clone as 17703-1-PBS)

    IF Staining of U2OS using 17703-1-AP (same clone as 17703-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using REV1 antibody (17703-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 17703-1-PBS in a different storage buffer formulation.

REV1 Polyclonal antibody, PBS Only

REV1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 17703-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

17703-1-PBS targets REV1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag11975

Product name: Recombinant human REV1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 764-1114 aa of BC037734

Sequence: SRPSVQSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTSPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISGWLGLC

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 REV1 homolog (S. cerevisiae)
别名
计算分子量 1114 aa, 122 kDa
观测分子量140-150 kDa
GenBank蛋白编号BC037734
基因名称 REV1
Gene ID (NCBI) 51455
RRIDAB_3085535
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UBZ9
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Rev1 is a member of the TLS polymerase family and plays a key role in this mutagenic pathway, which allows the bypass of modified DNA bases and respectively, facilitates proliferation even in the presence of extensive DNA damage, such as during chemotherapy. Mutations in human REV1 have been detected in a minority of tumors, and single-nucleotide polymorphisms (SNPs) in the hREV1 gene have been linked to various types of human cancer.

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