验证数据展示
产品信息
67395-1-PBS targets RBMS2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag27721 Product name: Recombinant human RBMS2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-407 aa of BC027863 Sequence: MLLSVTSRPGISTFGYNRNNKKPYVSLAQQMAPPSPSNSTPNSSSGSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTALQNGFYPAPYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSGSVLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAAAMQGAYISQYTPVPSSSVSVEESSGQQNQVAVDAPSEHGVYSFQFNK 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | RNA binding motif, single stranded interacting protein 2 |
| 别名 | 1E5C5, RNA-binding motif, single-stranded-interacting protein 2, SCR3, Suppressor of CDC2 with RNA-binding motif 3 |
| 计算分子量 | 407 aa, 44 kDa |
| 观测分子量 | 44 kDa |
| GenBank蛋白编号 | BC027863 |
| 基因名称 | RBMS2 |
| Gene ID (NCBI) | 5939 |
| RRID | AB_2882639 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q15434 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RBMS2 (RNA-binding motif, single-stranded-interacting protein 2), also known as SCR3 (Suppressor of CDC2 with RNA-binding motif 3), is a member of c-Myc single-strand binding proteins (MSSPs) family and encodes RNA binding protein. RBMS2 plays a critical role in the regulation of transcription and alternative splicing, both key cellular processes related to cell proliferation and programmed cell death or apoptosis (PMID: 40854446). Overexpression of RBMS2 inhibited CRC cell proliferation, migration, and epithelial-mesenchymal transition (EMT) (PMID: 30514345, 38058408).





