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RBM10 Polyclonal antibody
RBM10 Polyclonal Antibody for IF-P, IP, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IF-P, IP, WB, ELISA and More (3)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | human brain tissue |
| Positive IP detected in | mouse brain tissue |
| Positive IF detected in | mouse brain tissue |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
14423-1-AP targets RBM10 in WB, IP, IF, RIP, IHC, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | IF-P, IP, WB, ELISA |
| Cited Applications | WB, IP, IF, RIP, IHC, CoIP |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Immunogen | RBM10 fusion protein Ag5788 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | RNA binding motif protein 10 |
| Synonyms | DXS8237E, GPATC9, GPATCH9, KIAA0122, RBM10, RNA binding motif protein 10, RNA binding protein 10, RNA binding protein S1 1, S1 1, ZRANB5 |
| Calculated Molecular Weight | 104 kDa |
| Observed Molecular Weight | 115 kDa |
| GenBank Accession Number | BC024153 |
| Gene Symbol | RBM10 |
| Gene ID (NCBI) | 8241 |
| RRID | AB_2175593 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P98175 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
RBM10, also named as RNA-binding protein 10, is a 930 amino acid protein, which is in the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. RBM10 may be involved in post-transcriptional processing, most probably in mRNA splicing. RBM10 has some isoforms with MV 130 and 115 kDa (PMID: 25889998 and PMID: 18315527) .
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for RBM10 antibody 14423-1-AP | Download protocol |
| IF protocol for RBM10 antibody 14423-1-AP | Download protocol |
| IP protocol for RBM10 antibody 14423-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Proc Natl Acad Sci U S A RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5
| ||
Oncogene RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.
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BMC Mol Biol Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA.
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J Cell Mol Med RBM10 inhibits cell proliferation of lung adenocarcinoma via RAP1/AKT/CREB signalling pathway. | ||
Exp Cell Res RBM10 regulates the tumorigenic potential of human cancer cells by modulating PPM1B and YBX1 activities
| ||
Cancer Cell Int RBM10 regulates alternative splicing of lncRNA Neat1 to inhibit the invasion and metastasis of NSCLC
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