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验证数据展示

  • IHC staining of human pancreas cancer using 55326-1-AP

    IHC staining of human pancreas cancer using 55326-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 55326-1-AP (QSER1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human pancreas cancer using 55326-1-AP

    IHC staining of human pancreas cancer using 55326-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 55326-1-AP (QSER1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human lung cancer using 55326-1-AP

    IHC staining of human lung cancer using 55326-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 55326-1-AP (QSER1 antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human lung cancer using 55326-1-AP

    IHC staining of human lung cancer using 55326-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 55326-1-AP (QSER1 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IF Staining of HeLa using 55326-1-AP

    IF Staining of HeLa using 55326-1-AP

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using QSER1 antibody (55326-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2).

QSER1 Polyclonal antibody

QSER1 Polyclonal Antibody for IHC, IF/ICC, ELISA
Cat No. 55326-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, IF/ICC, ELISA

别名

glutamine and serine rich 1

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive IHC detected inhuman pancreas cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inHeLa cells

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

55326-1-AP targets QSER1 in IHC, IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, ELISA Application Description
经测试反应性 human
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 glutamine and serine rich 1
别名 glutamine and serine rich 1
计算分子量 190 kDa
GenBank蛋白编号NM_001076786
基因名称 QSER1
Gene ID (NCBI) 79832
RRIDAB_3743205
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ2KHR3
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

QSER1, a recently characterized protein, whose activity has been tightly associated with the protection of DNA methylation sites in hESCs. QSER1 is widely up-regulated in multiple cancers, and its up-regulation correlates with poor clinic outcomes (PMID: 36371602). QSER1 depletion leads to NODAL de-repression and associates with increased RNA Polymerase II occupancy at YAP1bound enhancers, pointing to a QSER1 contribution maintaining low transcriptional activity on certain genomic regions (PMID: 33833093, 35210841).

实验方案

Product Specific Protocols
IF protocol for QSER1 antibody 55326-1-APDownload protocol
IHC protocol for QSER1 antibody 55326-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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