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Host
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Species Reactivity
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验证数据展示

  • FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

    FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98414-4-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

    FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98414-4-PBS in a different storage buffer formulation.

Anti-Human Prion protein PrP/CD230 Rabbit Recombinant Antibody, PBS Only

Prion protein PrP/CD230 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98414-4-PBS

产品说明书

CloneNo. 243104D11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

Prion protein PrP, PRNP, PrP, Alternative prion protein, AltPrP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy PRNP Ready-To-Use IHC Kit. PRNP primary antibody included.

产品信息

98414-4-PBS targets Prion protein PrP/CD230 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Prion protein PrP/CD230 fusion protein Eg3359 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 prion protein
别名 Prion protein PrP, PRNP, PrP, Alternative prion protein, AltPrP
GenBank蛋白编号BC012844
基因名称 PrP
Gene ID (NCBI) 5621
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP04156
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The major prion protein (PrP), also known as CD230, is encoded by the prion protein-encoding gene (PRNP). PrP is widely expressed in a variety of tissues and is abundant in the nervous system and participates in neuronal growth and survival. PrP expression is strongly associated with immune infiltrating cells, immunosuppressive cell infiltration and immune checkpoint molecules. PrP is an immune-related prognostic marker that holds promise for predicting outcomes related to colorectal cancer immunotherapy.