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Host
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Species Reactivity
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验证数据展示

  • WB analysis of mouse skin using 85217-4-RR (same clone as 85217-4-PBS)

    WB analysis of mouse skin using 85217-4-RR (same clone as 85217-4-PBS)

    mouse skin tissue were subjected to SDS PAGE followed by western blot with 85217-4-RR (Plakophilin 1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85217-4-PBS in a different storage buffer formulation.

  • WB analysis using 85217-4-RR (same clone as 85217-4-PBS)

    WB analysis using 85217-4-RR (same clone as 85217-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85217-4-RR (Plakophilin 1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85217-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85217-4-RR

    Affinity and Kinetic Characterization of 85217-4-RR

    Biolayer interferometry (BLl) kinetic assays of 85217-4-RR against Human Plakophilin 1 were performed. The affinity constant is 11.4 nM.

Plakophilin 1 Recombinant antibody, PBS Only

Plakophilin 1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85217-4-PBS

产品说明书

CloneNo. 242834G8

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

PKP1, 242834G8, B6P, Plakophilin-1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85217-4-PBS targets Plakophilin 1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 Plakophilin 1 fusion protein Ag18153 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
别名 PKP1, 242834G8, B6P, Plakophilin-1
计算分子量 747 aa, 83 kDa
观测分子量70-75 kDa
GenBank蛋白编号BC114571
基因名称 PKP1
Gene ID (NCBI) 5317
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13835
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Plakophilin 1, also known as PKP1, B6P, is a member of the arm-repeat protein family. PKP1 contains arm-repeat (armadillo) domains, localizes to nuclei and cell desmosomes, and participates in linking cadherins to intermediate filaments in the cytoskeleton (PMID: 10747098). PKP1 contributes to epidermal morphogenesis and facilitates the formation of intermediate filaments. Mutations in PKP1 have been associated with the ectodermal dysplasia/skin fragility syndrome (PubMed:9326952, 10852826).