验证数据展示
Planning an IHC experiment? We recommend our IHCeasy Vimentin Ready-To-Use IHC Kit. Vimentin primary antibody included.
产品信息
87149-1-PBS targets Phospho-Vimentin (Ser56) in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | vimentin |
| 别名 | Phospho Vimentin, Phospho Vimentin (Ser56), Phospho-VIM (Ser56), Phospho-Vimentin, Phospho-Vimentin(Ser56) |
| 计算分子量 | 54 kDa |
| 观测分子量 | 57 kDa |
| GenBank蛋白编号 | NM_003380 |
| 基因名称 | VIM |
| Gene ID (NCBI) | 7431 |
| ENSEMBL Gene ID | ENSG00000026025 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P08670 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Vimentin, also named as VIM, belongs to the intermediate filament family. Phospho-Vimentin (Ser56) is a phosphorylated form of the intermediate filament protein Vimentin that plays a significant role in regulating cellular functions such as smooth muscle contraction, cell migration, and mitosis. Phosphorylation of Vimentin at Ser-56 has been found to regulate vimentin depolymerization and the spatial reorientation of vimentin filaments, which modulates intercellular force transmission and contraction in smooth muscle. (PMID: 27457922)
